Viridicatumtoxins: Expanding on a Rare Tetracycline Antibiotic Scaffold
收藏Figshare2016-02-12 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Viridicatumtoxins_Expanding_on_a_Rare_Tetracycline_Antibiotic_Scaffold/2097466
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资源简介：
Viridicatumtoxins, which belong to a rare class of fungal tetracycline-like mycotoxins, were subjected to comprehensive spectroscopic and chemical analysis, leading to reassignment/assignment of absolute configurations and characterization of a remarkably acid-stable antibiotic scaffold. Structure activity relationship studies revealed exceptional growth inhibitory activity against vancomycin-resistant Enterococci (IC50 40 nM), >270-fold more potent than the commercial antibiotic oxytetracycline.
创建时间：
2016-02-12
