Drug dissolution behaviour using liquid crystalline lipids

The structure and morphology patterns of coated hydrophilic (sodium salicylate) and hydrophobic (triamcinolone acetonide) was confirmed by using small angle x-ray scattering (SAXS) obtained within a 15 minute interval. This method is used for studying liquid crystalline structure in self assembled lipid systems, which is very sensitive to modification of both dimension and identify of phase structure(s).本研究采用小角度X射线散射（Small Angle X-ray Scattering, SAXS）技术，通过分析15分钟内采集的散射数据，证实了被包覆的亲水性物质（水杨酸钠，sodium salicylate）与疏水性物质（曲安奈德，triamcinolone acetonide）的结构与形貌模式。该方法可用于研究自组装脂质体系中的液晶结构，其对相结构的尺寸与相类型的变化均具有极强的敏感性。