CryoEM structure of the type IV pilin PilA5 from Thermus thermophilus

CryoEM structure of the type IV pilin PilA5 from Thermus thermophilus Descriptor: 7-Acetamido-5-acetimidoyl-3,5,7,9-tetradeoxy-L-glycero-L-manno-nonulosonic aci-(1-4)-alpha-D-mannopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose, MAGNESIUM ION, Type IV narrow pilus major component PilA5 Authors: Gold, V.A.M, Neuhaus, A, Gaines, M, Isupov, M, McLaren, M. Deposit date: 2023-10-04 Release date: 2024-10-16 Last modified: 2026-04-22 Method: ELECTRON MICROSCOPY (2.63 Å) Cite: Structural insights into the Thermus thermophilus type IV pilus machinery assembling two distinct pili. Commun Biol, 9, 2026嗜热栖热菌（Thermus thermophilus）IV型菌毛蛋白PilA5的冷冻电镜（CryoEM）结构 结构描述：7-乙酰氨基-5-乙酰亚胺基-3,5,7,9-四脱氧-L-甘油-L-甘露-壬酮糖-(1→4)-α-D-吡喃甘露糖-(1→3)-2-乙酰氨基-2-脱氧-α-D-吡喃半乳糖-(1→3)-2-乙酰氨基-2-脱氧-α-D-吡喃半乳糖、镁离子（MAGNESIUM ION），该组分对应IV型窄菌毛主要成分PilA5。 作者：Gold, V.A.M.、Neuhaus, A.、Gaines, M.、Isupov, M.、McLaren, M. 存储日期：2023-10-04；发布日期：2024-10-16；最后修改日期：2026-04-22 实验方法：电子显微镜（分辨率2.63 Å） 引用文献：《嗜热栖热菌组装两种不同菌毛的IV型菌毛机器的结构解析（Structural insights into the Thermus thermophilus type IV pilus machinery assembling two distinct pili）》，发表于《通讯生物学（Communications Biology）》，第9卷，2026年