Salmonella typhimurium Tryptophan Synthase beta-S377A mutant in complex with inhibitor F9 at the enzyme alpha-site, cesium ion at the metal coordination site and carbanion III E(C3) at the enzyme beta-site.

Salmonella typhimurium Tryptophan Synthase beta-S377A mutant in complex with inhibitor F9 at the enzyme alpha-site, cesium ion at the metal coordination site and carbanion III E(C3) at the enzyme beta-site. Descriptor: (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-3-[(2-hydroxyphenyl)amino]propanoic acid, 1,2-ETHANEDIOL, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, ... Authors: Hilario, E, Dunn, M.F, Mueller, L.J, Fan, L. Deposit date: 2020-06-11 Release date: 2021-03-10 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Salmonella typhimurium Tryptophan Synthase beta-S377A mutant in complex with inhibitor F9 at the enzyme alpha-site, cesium ion at the metal coordination site and carbanion III E(C3) at the enzyme beta-site. To be Published

鼠伤寒沙门氏菌（Salmonella typhimurium）色氨酸合酶（Tryptophan Synthase）β亚基S377A突变体，与结合于酶α位点的抑制剂F9、金属配位位点的铯离子以及结合于酶β位点的碳负离子III E(C3)形成复合物。配体描述：(2E)-2-[({3-羟基-2-甲基-5-[(膦酰氧基)甲基]吡啶-4-基}甲基)亚氨基]-3-[(2-羟基苯基)氨基]丙酸、1,2-乙二醇、2-({[4-(三氟甲氧基)苯基]磺酰基}氨基)乙基二氢磷酸酯…… 作者：Hilario E、Dunn M.F、Mueller L.J、Fan L。提交日期：2020-06-11，发布日期：2021-03-10，末次修改日期：2023-10-18。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.55埃（Å）。引用说明：鼠伤寒沙门氏菌色氨酸合酶β亚基S377A突变体与酶α位点抑制剂F9、金属配位位点铯离子及酶β位点碳负离子III E(C3)形成的复合物，待发表。