Mtb GuaB dCBS in complex with inhibitor compound 5
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Mtb GuaB dCBS in complex with inhibitor compound 5 Descriptor: (3P)-3-(4-chloro-1H-imidazol-2-yl)-5-[(1R)-1-{[(3M)-3-(1H-pyrazol-5-yl)phenyl]oxy}ethyl]pyridine, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase Authors: Harris, S.F, Wu, P. Deposit date: 2024-08-25 Release date: 2024-11-27 Last modified: 2025-01-29 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of potent dihydro-oxazinoquinolinone inhibitors of GuaB for the treatment of tuberculosis. Bioorg.Med.Chem.Lett., 117, 2025
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2024-08-25
