Horse liver alcohol dehydrogense His-51-Gln form complexed with NADH and N-cyclohexylformamide

Horse liver alcohol dehydrogense His-51-Gln form complexed with NADH and N-cyclohexylformamide Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alcohol dehydrogenase E chain, ... Authors: Plapp, B.V. Deposit date: 2023-02-07 Release date: 2023-02-15 Last modified: 2024-09-04 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Histidine-51 facilitates deprotonation of the zinc-bound ligand during catalysis by horse liver alcohol dehydrogenase To Be Published

本数据集为马肝醇脱氢酶（Horse liver alcohol dehydrogenase）His-51→谷氨酰胺突变体与1,4-二氢烟酰胺腺嘌呤二核苷酸（NADH）及N-环己基甲酰胺形成的复合物。描述项：(4R)-2-甲基戊烷-2,4-二醇、1,4-二氢烟酰胺腺嘌呤二核苷酸、醇脱氢酶E链…… 作者：Plapp, B.V. 提交日期：2023-02-07 发布日期：2023-02-15 最后修改日期：2024-09-04 实验方法：X射线衍射（分辨率1.42埃） 引用说明：组氨酸-51在马肝醇脱氢酶的催化过程中可促进锌结合配体的去质子化反应，该成果待发表。