Comparison of human NK and T cell microRNAs

We studied the levels of expression of hundreds of mature miRNA's on an arrray (miRCURY, Exiqon, Cophenhagen, DN) for primary human T cells and NK cells. We found a 4% difference in the level of expression between these two cell types. NK and T cells were purified from peripheral blood mononuclear cells by negative selection from three healthy adult individuals, and total RNA was harvested. Samples reverse transcribed and studied on a microarry (miRCURY, Exiqon)