(A) EC50 for Hydrogen Peroxide.

Raw data used to generate the EC₅₀ values shown in Fig 3B. Column A indicates the H₂O₂ concentrations used in the assay, while columns B to J contain the relative growth data from each replicate for the three T. cruzi populations. (B) EC₅₀ for Benznidazole. Raw data used to generate the EC₅₀ values shown in Fig 3A. Column A indicates the benznidazole concentrations used in the assay, while columns B to J contain the relative growth data from each replicate for the three T. cruzi populations. (C) Infected fibroblasts. Raw data used to generate the infectivity values shown in Fig 4A. Column A indicates the percentage of infected L929 cells, while columns B to G contain the percentage of infected fibroblasts recorded in each assay, performed in two replicates for the three T. cruzi populations. (D) Amastigotes in 100 cells. Raw data used to generate the infectivity values shown in Fig 4B. Column A indicates the number of intracellular amastigotes in infected L929 cells, while columns B to G contain the mean number of amastigotes per 100 L929 cells recorded in each assay, performed in two replicates for the three T. cruzi populations. (E) RT-qPCR. Raw data used to generate the transcript level values shown in Fig 1B. Column A lists the genes analyzed (GAT1, GAT2, and GAT3), while columns B to J contain the relative quantification data for each replicate from the three T. cruzi populations. (F) Genomic qPCR. Raw data used to generate the gene copy number values shown in Fig 1A. Column A lists the genes analyzed (GAT1, GAT2, and GAT3), while columns B to J contain the relative genomic quantification data from each replicate of the three T. cruzi populations. (G) Growth curve. Raw data used to generate the growth curve shown in S3 Fig. Column A indicates the 10 days of the experiment, while columns B to J contain the mean number of epimastigote forms counted in each assay, performed in three replicates for the three T. cruzi populations. (XLSX)