Data for "A hippocampus-accumbens code guides goal-directed appetitive behavior"

This dataset represents the source data for the manuscript "A hippocampus-accumbens code guides goal-directed appetitive behavior" by Barnstedt, Mocellin, and Remy. All files are saved as dataframes with pandas (v1.4.3, using 'blosc' compression for H5).

It contains the following files:

ArchT.feather

Dataframe containing all source behavioural data for mice expressing ArchT in NAc-projecting dHPC neurons. 10 mice in ArchT/EYFP groups are tested for 8 days on a head-fixed spatial reward learning task. 100 Hz temporal resolution.

behaviour.h5
Dataframe containing all source behavioural data accompanying calcium imaging, collected from analogue signals and camera signals, downsampled to 15/30 Hz to match imaging temporal resolution.

C.h5
Deconvolved calcium signals from 5372 dHPC pyramidal neurons recorded at 15/30 Hz in Thy1-GCaMP6s mice. Data collected with two-photon imaging and extracted using CaImAn.

ChR.feather
Dataframe containing all source behavioural data for mice expressing ChR2 in dHPC axons in NAc. 7 mice in ChR2/EYFP groups are tested over several days while naive and during a head-fixed spatial reward learning task. 75 Hz temporal resolution.

comps.feather
Dataframe containing one row per neuron, showing diverse neuronal features.

psth_ds.feather
Dataframe with peri-stimulus time histograms of calcium activity around lick onsets.

S.h5
Deconvolved calcium events from 5372 dHPC pyramidal neurons recorded at 15/30 Hz in Thy1-GCaMP6s mice. Data collected with two-photon imaging and extracted using CaImAn.

success_comreward.feather
Dataframe showing successful behavioural trials with percentage of dHPC-/dHPC-->NAc neurons with place field centers near the reward zone.

training.feather
Dataframe containing all source behavioural data without calcium imaging, collected from analogue signals and camera signals, collected at 25/75 Hz from 18 mice.