相关数据集
Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition [miRNA]
Treatment of leukemia cells with 1,25-dihydroxyvitamin D3 may overcome their differentiation block and lead to the transition from myeloblasts to monocytes. To identify microRNA-mRNA networks relevant
NIAID Data Ecosystem60
Long Intergenic Non-Coding RNA HOTAIRM1 Regulates Cell Cycle Progression During Myeloid Maturation in NB4 Promyelocytic Leukemia Cells
HOTAIRM1 is a long intergenic non-coding RNA located in the human HOXA gene cluster, with gene expression highly specific for maturing myeloid cells, particularly during all-trans retinoic acid (ATRA)
NIAID Data Ecosystem40
Comparing The Transcriptomes of Granulocytic and Macrophage Differentiated Forms of HL-60/S4 Cells. Homo sapiens
The acute myeloblastic leukemia cell line HL-60 can be differentiated in vitro from a rapidly growing promyelocytic form to a nongrowing form, resembling neutrophils with segmented (lobulated) nuclei,
NIAID Data Ecosystem30
Zinc finger protein 521 overexpression is a feature of MLL-rearranged acute myeloid leukemia and contributes to the maintenance of myeloid differentiation block
ZNF521 is a multiple zinc finger transcription factor previously identified because abundantly and selectively expressed in normal CD34+ hematopoietic stem and progenitor cells. From microarray datase
NIAID Data Ecosystem50
Reprogramming leukemic cells to terminal differentiation by inhibiting specific cyclin-dependent kinases in G(1)
Some tumor cells can be stimulated to differentiate and undergo terminal cell division and loss of tumorigenicity. The in vitro differentiation of murine erythroleukemia (MEL) cells is a dramatic exam
PubMed Central2000-12-12 更新30
