Crystal structure of human Sirt2 in complex with SirReal2

Crystal structure of human Sirt2 in complex with SirReal2 Descriptor: 1,2-ETHANEDIOL, 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide, CHLORIDE ION, ... Authors: Friedrich, F, Einsle, O, Jung, M. Deposit date: 2024-05-17 Release date: 2025-05-28 Last modified: 2025-06-25 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Efficient Crystallization of Apo Sirt2 for Small-Molecule Soaking and Structural Analysis of Ligand Interactions. J.Med.Chem., 68, 2025