RNA Sequencing Analysis of JFK-overexpressing and ING5-depleted HepG2 cells

To explore the functional significance of JFK-mediated ING5 degradation, we performed genome-wide analysis of the transcriptome in hepatocytes that is regulated by the JFK-ING5 axis using RNA-based deep sequencing (RNA-seq). The data obtained from RNA-seq experiments were cross-analyzed with ChIP-seq data of ING5 from HepG2 cells. Overall design: RNA-seq from HepG2 cells transfected with vector or JFK or treated with control or ING5 siRNAs