MOESM1 of Substrates and oxygen dependent citric acid production by Yarrowia lipolytica: insights through transcriptome and fluxome analyses

Additional file 1. Figure S1. Biomass, products formation and substrate consumption in a pO2 uncontrolled culture of Y. lipolytica grown on a mixture of glycerol and spruce biomass hydrolysate. Figure S2. Gene ontology analysis of differentially expressed genes compared between pO2 controlled before vs. after glycerol limitation. Figure S3. Gene ontology analysis of differentially expressed genes compared between pO2 uncontrolled before vs. after glycerol limitation. Figure S4. Significant pathways and enzymes in the central metabolism of Y. lipolytica showing the differential gene expression between cell samples taken at pO2 controlled conditions before and after glycerol limitation (arrow). Figure S5. Flux distribution of Y. lipolytica grown on glycerol and glucose with pO2 control. Values are in mmol g DCW −1 h−1 normalized to glycerol uptake rate which is set as 100%. Arrows indicated flux towards biomass precursors.