Hepatic lipids in liver from PND80 male rats at baseline (INTACT), without (−CH) or with (+CH) transient neonatal exposure to MMI, during thyroid hormone deprivation (vehicle) and hormonal replacement.

INTACT and CH animals were exposed to MMI at PND60 as described in Materials and Methods. From day 73, animals were injected daily with vehicle, T3 or GH for 7 d. The animals were sacrificed on PND80 and hepatic lipids were measured. Results are expressed as mean ± SD (n = 6). Statistical comparison was performed for treated animals using INTACT animals or vehicle as controls.
*
, P<0.05;
**
, P<0.01;
***
, P<0.001 for comparison with INTACT rats;
+
, P<0.05;
++
, P<0.01 for comparison with vehicle.