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Transcriptome profiling in knock-in mouse models of Huntington's disease (cortex_mRNA).

ChEBI2016-02-24 更新2026-07-12 收录

亨廷顿病分子机制

神经退行性疾病

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-78272 数据链接链接失效反馈

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资源简介：

Transcriptome profiling in knock-in mouse models of Huntington's disease (cortex_mRNA).

应用场景：

创建时间：

2016-02-24

神经退行性疾病

自噬

Lysosomal membrane permeabilization (LMP) is observed under many pathological conditions, leading to cellular dysfunction and death. However, the mechanisms by which lysosomal membranes become leaky <

DataCite Commons2021-05-08 更新90

In vitro assembled 266/297 - 391 tau filaments with KCl (10b)

tau蛋白纤维结构

神经退行性疾病

In vitro assembled 266/297 - 391 tau filaments with KCl (10b) Descriptor: Microtubule-associated protein tau Authors: Lovestam, S, Scheres, S.H.W. Deposit date: 2022-02-10 Release date: 2022-02-23 Las

Protein Data Bank Japan2024-07-17 更新40

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (RNA-seq). Mus musculus

亨廷顿病分子机制

表观遗传调控

Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain.

NIAID Data Ecosystem30

Saliva Neurofilament Light Chain Is Not a Diagnostic Biomarker for Neurodegeneration in a Mixed Memory Clinic Population

神经退行性疾病

生物标志物

Saliva Neurofilament Light Chain Is Not a Diagnostic Biomarker for Neurodegeneration in a Mixed Memory Clinic Population

Global Health Data Exchange ()50

Distribution patterns of α-syn-positive neurons in subcortical structures.

α-突触核蛋白分布图谱

神经退行性疾病

-, none; +, sparse (1-10/ROI); ++, moderate (11-20/ROI); +++, dense (21-/ROI). Amy, amygdala; Hip, hippocampus; LS, lateral septum; m, months; NA, nucleus accumbens; RRF, retrorubral field; SNc, subst

NIAID Data Ecosystem40

Transcriptome profiling in knock-in mouse models of Huntington's disease (cortex_mRNA).

资源简介：

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