PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P07E01 from the F2X-Universal Library

PanDDA analysis group deposition -- Aar2/RNaseH in complex with fragment P07E01 from the F2X-Universal Library Descriptor: (3S)-3-methyl-5-oxo-5-[(1,3-thiazol-2-yl)amino]pentanoic acid, A1 cistron-splicing factor AAR2, Pre-mRNA-splicing factor 8 Authors: Barthel, T, Wollenhaupt, J, Lima, G.M.A, Wahl, M.C, Weiss, M.S. Deposit date: 2022-08-26 Release date: 2022-11-02 Last modified: 2024-05-22 Method: X-RAY DIFFRACTION (1.51 Å) Cite: Large-Scale Crystallographic Fragment Screening Expedites Compound Optimization and Identifies Putative Protein-Protein Interaction Sites. J.Med.Chem., 65, 2022

PanDDA分析工作组提交存档——与F2X通用文库片段P07E01结合的Aar2/RNaseH复合物，描述符：(3S)-3-甲基-5-氧代-5-[(1,3-噻唑-2-基)氨基]戊酸、A1顺式剪接因子AAR2、前mRNA剪接因子8。作者：Barthel, T、Wollenhaupt, J、Lima, G.M.A、Wahl, M.C、Weiss, M.S。提交日期：2022-08-26；发布日期：2022-11-02；最后修改日期：2024-05-22。实验方法：X射线衍射（分辨率1.51埃）。引用文献：《大规模晶体学片段筛选加速化合物优化并鉴定潜在蛋白质-蛋白质相互作用位点》，《药物化学杂志》（J.Med.Chem.），第65卷，2022年。