TNF-signaling modulates neutrophil-mediated immunity at the feto-maternal interface during LPS-induced intrauterine inflammation
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https://www.ncbi.nlm.nih.gov/sra/SRP250720
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We demonstrate that anti-TNF antibody (Adalimumab) inhibited ~80% of highly LPS-induced genes that sub-serve inflammatory signaling and innate immunity in chorio-decidua neutrophils. Overall design: RNAseq of purified blood maternal neutrophils vs. FACS-sorted chorio-decidua neutrophils in a Rhesus model of intrauterine infection/inflammation
创建时间：
2020-04-28
