USP2 inhibition prevents infection with ACE2- dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice
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https://www.ncbi.nlm.nih.gov/sra/SRP450308
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资源简介：
In this study, we identified USP2 as a physiological deubiquitinase of ACE2 and USP2 inhibition led to ACE2 protein destruction, thereby preventing infections of coronaviruses that reliant on ACE2 Overall design: RNA-seq study of lung samples derived from K18-hACE2 mice infected with SARS-CoV-2 (Wuhan strain) and subjected to the treatment of vehicle control or USP2 inhibitor ML364
创建时间：
2023-12-09
