Precise genetic control of ATOH1 enhances maturation of regenerated hair cells in mouse utricle

NIAID Data Ecosystem2026-05-02 收录

内耳毛细胞再生

ATOH1基因调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE251854 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2024-12-04

Table_1_Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea.pdf

内耳毛细胞再生

前体细胞比较研究

Hair cell (HC) loss is irreversible because only very limited HC regeneration has been observed in the adult mammalian cochlea. Wnt/β-catenin signaling regulates prosensory cell proliferation and diff

NIAID Data Ecosystem110

DNA methylation in the mouse cochlea promotes maturation of supporting cells and contributes to the failure of hair cell regeneration

内耳毛细胞再生

耳蜗支持细胞表观遗传组学

Purpose - To profile epigenetic changes in cochlear progenitor cells, hair cells, and supporting cells across postnatal development. Methods- Cochlear cell types were obtained from fluorescently la

NIAID Data Ecosystem70

Table_3_Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris.xlsx

内耳毛细胞再生

前庭神经生物学

The mechanism underlying hair cell (HC) regeneration in the mammalian inner ear is still under debate. Understanding what molecules regulate the HC regeneration in mature mammals will be the key to th

NIAID Data Ecosystem50

Generation of Inner Ear Hair Cells by Direct Lineage Conversion of Primary Somatic Cells. Generation of Inner Ear Hair Cells by Direct Lineage Conversion of Primary Somatic Cells

内耳毛细胞再生

直接谱系转换

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem70

Gallus gallus utricle striola vs. extra-striola. Gallus gallus

内耳毛细胞再生

听觉遗传学通路

The inner ear utilizes sensory hair cells as mechano-electric transducers for sensing sound and balance. In mammals, these hair cells lack the capacity for regeneration. Unlike mammals, hair cells fro

NIAID Data Ecosystem50

Precise genetic control of ATOH1 enhances maturation of regenerated hair cells in mouse utricle

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