HNF1A, H3K4me3 and H3K27ac ChIP-seq in control and Haster-deficient mouse livers. HNF1A, H3K4me3 and H3K27ac ChIP-seq in control and Haster-deficient mouse livers
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
The HASTER promoter region is a cis-regulatory element that stabilizes the transcription of HNF1A, preventing silencing or overexpression. We have generated a mouse model where the promoter of Haster has been specifically deleted in liver (Haster loxP/loxP; AlbCre). In liver the prevailing consequence is upregulation of HNF1A. We performed HNF1A, H3K4me3 and H3K27ac ChIP-seq to assess the impact of HNF1A upregulation on the chromatin landscape of Haster KO liver.
创建时间：
2022-05-20
