ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq]. Homo sapiens

We report that H2B deubiquitinating enzymes USP22, USP27x and USP51 have both unique and overlapping target loci. Overall design: Comparing gene expression profiles of MCF7 cells stably expressing shRNA targeting either USP22, USP27X or USP51 and cells expressing non-targeting shRNA.