Global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines investigated by UPLC-MS/MS
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We performed UPLC-MS/MS to investigate global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines (97L and LM6 cells). We found that 5mC and 5hmC were frequently decreased in 71% and 100% of the HCC specimens, respectively, compared with non-HCC specimens. Correspondingly, 5mC and 5hmC levels in the two HCC cell lines remained relatively low.
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2016-01-19



