Synthetic dataset 2

Synthetic dataset of nuclei on a tube-like tissue that changes shape, for analysis demonstration with TubULAR. <br> TubULAR is a set of tools for working with 3D data of surfaces – potentially complex and dynamic – that can be described as tubes. Developing guts, pumping hearts, and other visceral organs can be treated as tubes with potentially complex and dynamic shapes. With TubULAR, we can describe the tissue motion on the tube-like surface and quantify how it changes over time. <br> This synthetic dataset is a tube of cells with nuclei and membrane that coils into a loop, then uncoils into a straight tube. To generate the dataset, the surface geometry was encoded numerically. We placed 120 nuclei-like blobs of intensity centered at locations across the surface. Locations were chosen as a solution to an iterative farthest-point search, so that nuclei are well-spaced from each other. We then performed a Voronoi tessellation to create a channel mimicking `cell-cell junctions'. The nuclei sizes were determined based on the distance of each nucleus to the nearest membrane location. <br> For more on the codebase, visit: https://npmitchell.github.io/tubular/ https://github.com/npmitchell/tubular