HILIC metabolomics for intracellular metabolite in Candida albican with or without short chain fatty acids

Candida albicans SC5314 was grown under four conditions: 1) YPD at pH 5.0; 2) YPD with 50 mM acetic acid; 3) YPD with 50 mM propionic acid at pH 5.0; 4) YPD with 50 mM butyric acid at pH 5.0. Cultures were grown for 4 hours at 37C aerbobically with shaking. Cultures were harvested and the intracellular metabolome was extracted for HILIC metabolomics. There are four replicates per condition. The file contains metabolites name; m/z for the metabolite, retention time for metabnolite, raw peak area in each sample, normalized peak area for each sample, ratio of area under YPD samples/ SCFA treated samples, log2 fold change of YPD samples/SCFA treated samples, p value for the ratio of YPD samples/SCFA treated samples, adjusted p value of YPD samples/SCFA treated samples and VIP score本数据集以白色念珠菌（Candida albicans）SC5314为研究菌株，设置4种培养条件：1）pH 5.0的酵母浸出粉胨葡萄糖（YPD）培养基；2）添加50 mM乙酸的YPD培养基；3）pH 5.0且添加50 mM丙酸的YPD培养基；4）pH 5.0且添加50 mM丁酸的YPD培养基。所有培养体系均于37℃、有氧振荡条件下培养4小时。收集培养液后提取细胞内代谢组，用于亲水相互作用色谱（HILIC）代谢组学分析。每组设置4个生物学重复。该数据集文件包含以下信息：代谢物名称、代谢物质荷比（m/z）、代谢物保留时间、各样本的原始峰面积、各样本的归一化峰面积、YPD组与短链脂肪酸（SCFA）处理组的峰面积比值、YPD组相对于SCFA处理组的log₂折叠变化、上述峰面积比值的p值、校正后p值以及变量重要性投影（VIP）得分。