Transcriptional responses to interferon require Mediator kinase-dependent pause release and mechanistically distinct functions of CDK8 and CDK19. Transcriptional responses to interferon require Mediator kinase-dependent pause release and mechanistically distinct functions of CDK8 and CDK19

Transcriptional responses to interferon require Mediator kinase-dependent pause release and mechanistically distinct functions of CDK8 and CDK19. Overall design: Examination of 45 minute IFNgamma response in CDK8 analog sensitive HCT116 cells compared with wild type HCT116 cells with all the applicable controls.