Whole blood transcriptome in long-COVID patients reveals association with lung function and immune response. Whole blood transcriptome in long-COVID patients reveals association with lung function and immune response

It is estimated that 10% of COVID survivor still experience from complaints months after infection. Here we collected blood from 95 patients in the P4O2 COVID-19 study and performed RNA-seq at 3-6 months and 12-15 after infection. Our aim was to discover biomarkers related to long COVID and perform unsupervised clustering to potentially reveal pathological underlying mechanism for long COVID Overall design: Blood was collected and sequenced at 3-6 months and 12-15 months after infection in this observational study. No experimental treatments were performed. Additional clinical variables can be requested through the P4O2 data committee (via [e-mail]). For more info see https://pmc.ncbi.nlm.nih.gov/articles/PMC10381397/#notes4