five

Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE163088
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We report the application for high-throughput profiling of transcriptome, chromatin-associated proteins and histone-modifications on a genome-wide level in iPSC-derived family control astrocytes vs LFS (Li-Fraumeni Syndrome) patient astrocytes. RNA-seq, ChIP-seq, eCLIP-seq and m6Aseq are used to profile LFS patient derived astrocytes
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2023-04-03
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