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CD49f defines a subset of dysfunctional regulatory T cells circulating in the human peripheral blood

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NIAID Data Ecosystem2026-03-12 收录
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Integrin CD49f has been reported to modulate various aspects of T cell biology including cell differentiation, migration and functionality. Here we define CD49f as a marker for a subset of dysfunctional human effector Tregs expressing a Th17-like profile in the blood of patients with active inflammatory bowl disease. Overall design: RNA profiles of CD49f high and low Tregs extracted from healthy donor peripheral blood mononuclear cells (PBMC).

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2021-09-17
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