RNA-sequence analysis in periferal blood before and after direct antiviral agent treatment for chronic hepatitis C. RNA-sequence analysis in periferal blood before and after direct antiviral agent treatment for chronic hepatitis C

RNA-sequencing analysis exhibited different patterns of gene expression between SVR and non-SVR groups. Overall design: We isolated total RNA from peripheral blood mononuclear cells from 25 sustained virological response (SVR) cases before and after ombitasvir/paritaprevir/ritonavir treatment and 4 non-SVR cases.