Palladium(II)-Catalyzed Regioselective syn-Hydroarylation of Disubstituted Alkynes Using a Removable Directing Group
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://figshare.com/articles/dataset/Palladium_II_-Catalyzed_Regioselective_syn-Hydroarylation_of_Disubstituted_Alkynes_Using_a_Removable_Directing_Group/3851562
下载链接
链接失效反馈官方服务：
资源简介：
A palladium(II)-catalyzed
regioselective syn-hydroarylation
reaction of homopropargyl amines has been developed, wherein selectivity
is controlled by a cleavable bidentate directing group. Under the
optimized reaction conditions, both dialkyl and alkylaryl alkyne substrates
were found to undergo hydroarylation with high selectivity. The products
of this reaction contain a 4,4-disubstituted homoallylic amine motif
that is commonly seen in drug molecules and other bioactive compounds.
创建时间：
2016-09-30
