WP5482 - Oxidative stress in pulmonary tissue - Homo sapiens

NIAID Data Ecosystem2026-05-02 收录

肺组织氧化应激

不良结果路径

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https://www.ndexbio.org/viewer/networks/4329595b-1439-11f0-9806-005056ae3c32 数据链接链接失效反馈

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Adverse Outcome Pathway (AOP) for stressor induced increase in ROS production in pulmonary tissue.

创建时间：

2025-04-17

Frustrated phagocytosis leading to malignant pleural mesothelioma

胸膜间皮瘤

不良结果路径

Adverse Outcome Pathway for malignant pleural mesothelioma, known to be initiated by asbestos and carbon nanotubes. This molecular AOP is based on https://aopwiki.org/aops/409

wikipathways.github.io70

Adverse Outcome Pathway on Aromatase Inhibition Leading to Reproductive Dysfunction (in Fish)

生殖毒理学

不良结果路径

This adverse outcome pathway details the linkage between inhibition of gonadal aromatase activity in females and reproductive dysfunction, as measured through the adverse effect of reduced cumulative

Organisation for Economic Co-operation and Development60

Data_Sheet_1_Capturing a Comprehensive Picture of Biological Events From Adverse Outcome Pathways in the Drug Exposome.docx

药物安全性评估

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Background: The chemical part of the exposome, including drugs, may explain the increase of health effects with outcomes such as infertility, allergies, metabolic disorders, which cannot be only expla

NIAID Data Ecosystem50

Integration of multi-omics and benchmark dose modeling to support adverse outcome pathways

辐射生物学

不良结果路径

Recent advancements in omics and benchmark dose (BMD) modeling have facilitated identifying the dose required for a predetermined change in a response (e.g. gene or protein change) that can be used to

DataCite Commons2025-07-24 更新70

Deploying elements of scoping review methods for adverse outcome pathway development: a space travel case example

不良结果路径

人工智能

Health protection agencies require scientific information for evidence-based decision-making and guideline development. However, vetting and collating large quantities of published research to identif

DataCite Commons2023-03-06 更新50

WP5482 - Oxidative stress in pulmonary tissue - Homo sapiens

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