Signaling between mammalian adiponectin and a mosquito adiponectin receptor reduces Plasmodium transmission

In this study we determine the effects of silencing adiponectin receptor in A. gambiae mosquitoes after taking Plasmodium gambiae infected blood meals. dsRNA (dsAdpR and dsGluc) microinjected A. gambiae mosquitoes were fed on P. berghei-infected Swiss Webster mice. Two days after a blood meal, the mosquitoes were collected for midgut dissection. Overall design: Examination of the transcriptomic change in midguts after silencing adiponectin receptor