Pathway enrichment analysis of genes separated by principal components.

Signal transduction pathway associations of genes which are separated by principal component analysis after 4-h, 12-h, or 24-h treatment are depicted. Principal component one separates the effect of differentiation, whereas principal component two represents the effect of TNF-α treatment. Finally, principal component three separates the effect of IGF1 treatment versus control myotubes. Pathway enrichment was based on cocitation with a p value cutoff of Table 3.Pathway enrichment analysis of genes separated by principal components.