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资源简介:
22Rv1_AR_ENZ3w_1nM-DHT_rep2
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创建时间:
2023-03-09
相关数据集
Progesterone receptor genomic and transcriptomic effects are shaped by estrogen priming to produce a unique response in breast cancer cells
Introduction: Progesterone receptor (PR) is essential for normal breast homeostatic maintenance and is important for dynamic breast remodelling through the menstrual cycle and pregnancy. Furthermore,
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Cancer Stem Cell Phenotypes in ER + Breast Cancer Models Are Promoted by PELP1/AIB1 Complexes
Trascriptome analysis of mcf7 cell lines were performed MCF-7 PELP1 cells expressing LXSN, WT PELP1, or cytoplasmic (cyto) PELP1 were hormone-starved in modified IMEM containing 5% DCC for 16 hours pr
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Glucocorticoid Receptor: MegaTrans Switching Mediates Repression of ERα-Regulated Transcriptional Program [Gro-Seq]
The mechanisms underlying GR-dependent inhibition of ERα-regulated gene activation programs at the global genomic level have been poorly understood. We found the binding of GR in trans on ERα-activate
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Expression profiling by RNA-seq of LNCaP cells expressing wild-type androgen receptor (AR-WT), AR-V7 splice variant or mutant AR-Q641X. Expression profiling by RNA-seq of LNCaP cells expressing wild-type androgen receptor (AR-WT), AR-V7 splice variant or mutant AR-Q641X
The androgen receptor (AR) signaling remains the key therapeutic target in metastatic prostate cancer (PCa). However, development of castration resistant PCa is frequently observed and can be in part
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Gene expression data from treated LNCaP prostate cells.
Prostate cancer is dependent on androgen receptor (AR) signaling at all stages of the disease and cyclin D1 has been shown to negatively modulate the expression of the AR-dependent gene prostate speci
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