Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface.
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Large improvement in the thermal stability of a tetrameric malate dehydrogenase by single point mutations at the dimer-dimer interface. Descriptor: FUMARIC ACID, MALATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Bjork, A, Dalhus, B, Mantzilas, D, Eijsink, V.G.H, Sirevag, R. Deposit date: 2004-02-25 Release date: 2004-08-26 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Large Improvement in the Thermal Stability of a Tetrameric Malate Dehydrogenase by Single Point Mutations at the Dimer-Dimer Interface. J.Mol.Biol., 341, 2004
通过在二聚体-二聚体界面引入单点突变，可显著提升四聚体苹果酸脱氢酶（tetrameric malate dehydrogenase）的热稳定性。
关键词：延胡索酸（fumaric acid）、苹果酸脱氢酶（malate dehydrogenase）、烟酰胺腺嘌呤二核苷酸（nicotinamide-adenine-dinucleotide）
作者：Bjork, A、Dalhus, B、Mantzilas, D、Eijsink, V.G.H、Sirevag, R
提交日期：2004-02-25
发布日期：2004-08-26
末次修改日期：2023-12-13
实验方法：X射线衍射，分辨率1.9 Å
引用：通过二聚体-二聚体界面单点突变大幅提升四聚体苹果酸脱氢酶热稳定性. 《J.Mol.Biol.》, 341, 2004
创建时间：
2004-02-25
