ScRNA-seq Links Dental Fibroblasts Heterogeneity with Mechanoresponsiveness

Periodontal ligament (PDL) and dental pulp (DP) share a common origin but have distinct biological and mechanical functions. We used ScRNA-seq to decipher cellular heterogeneity and their underlying molecular mechanisms. A single-cell comparison of digested human periodontal ligament (PDL) and dental pulp (DP) was performed using scRNA-seq.