Data from: Silicone wristbands detect individuals' pesticide exposures in West Africa

We detected between 2 and 10 pesticides per person with novel sampling devices worn by 35 participants who were actively engaged in farming in Diender, Senegal. Participants were recruited to wear silicone wristbands for each of two separate periods of up to 5 days. Pesticide exposure profiles were highly individualized with only limited associations with demographic data. Using a 63-pesticide dual-column gas chromatography–electron capture detector (GC-ECD) method, we detected pyrethoid insecticides most frequently, followed by organophosphate pesticides which have been linked to adverse health outcomes. This work provides the first report of individualized exposure profiles among smallholder farmers in West Africa, where logistical and practical constraints have prevented the use of more traditional approaches to exposure assessment in the past. The wristbands and associated analytical method enabled detection of a broad range of agricultural, domestic, legacy and current-use pesticides, including esfenvalerate, cypermethrin, lindane, DDT and chlorpyrifos. Participants reported the use of 13 pesticide active ingredients while wearing wristbands. All six of the pesticides that were both reportedly used and included in the analytical method were detected in at least one wristband. An additional 19 pesticide compounds were detected beyond those that were reported to be in use, highlighting the importance of measuring exposure in addition to collecting surveys and self-reported use records. The wristband method is a candidate for more widespread use in pesticide exposure and health monitoring, and in the development of evidence-based policies for human health protection in an area where food security concerns are likely to intensify agricultural production and pesticide use in the near future.本研究针对塞内加尔迪恩德（Diender）地区35名活跃务农参与者开展农药暴露检测，受试者佩戴新型采样装置后，每人被检出接触2至10种农药。研究招募参与者在两个独立的、单次最长达5天的时段内佩戴硅胶腕带（silicone wristbands）。结果显示，农药接触谱呈现高度个体化特征，仅与人口统计学数据存在微弱关联。本研究采用覆盖63种农药的双柱气相色谱-电子捕获检测器（gas chromatography–electron capture detector, GC-ECD）分析方法，最常检出的成分为拟除虫菊酯类杀虫剂（pyrethoid insecticides），其次为与不良健康结局相关的有机磷农药。本研究首次报道了西非地区小农户（smallholder farmers）的个体化农药接触谱——此前由于后勤与实操限制，传统暴露评估方法难以在该地区应用。该硅胶腕带及配套分析方法可检测多种农业、民用、传统使用及当前在用的农药，包括乙氰菊酯（esfenvalerate）、氯氰菊酯（cypermethrin）、林丹（lindane）、滴滴涕（DDT）及毒死蜱（chlorpyrifos）。参与者报告在佩戴腕带期间使用了13种农药有效成分；分析方法覆盖且参与者报告使用过的6种农药，均至少在1条腕带样本中被检出。此外还额外检出19种未被报告使用的农药化合物，这凸显了除收集问卷与自我报告使用记录外，直接检测暴露情况的重要性。该腕带采样方法有望在农药暴露与健康监测领域得到更广泛应用，同时可为该地区制定循证的人类健康保护政策提供支持——未来粮食安全问题或将推动农业生产与农药使用量进一步提升。