GPCR-BSD

GPCR-BSD collects 127,990 predicted binding sites of 803 GPCRs under active and inactive states (thus 1,606 structures in total). The binding sites were identified from the predicted GPCR structures by executing three geometric-based pocket prediction methods, fpocket, CavityPlus and GHECOM. The server provides query, visualization, and comparison of the predicted binding sites for both GPCR predicted and experimentally determined structures recorded in PDB.GPCR-BSD数据集收录了803个G蛋白偶联受体（G Protein-Coupled Receptor，GPCR）在激活态与失活态下的127,990个预测结合位点，总计包含1606个结构。这些结合位点通过fpocket、CavityPlus与GHECOM三种基于几何的口袋预测方法，从预测获得的GPCR结构中识别得到。该服务器可针对PDB（Protein Data Bank）数据库中收录的GPCR预测结构与实验测定结构，提供其预测结合位点的查询、可视化及比对功能。