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Functional Variant at 19q13.3 Confers Nonsyndromic Cleft Palate Susceptibility by Regulating HIF3A

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NIAID Data Ecosystem2026-05-02 收录
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To explore the potential mechanisms in hif3a function in palatal tissues, we performed RNA-Seq of mouse embryonic palatal tissues overexpressing Hif3a and the control groups. Fetal mouse plate shelves were transfected with Hif3a overexpressing lentivirus and a non-targeting sequence to observe biological effects in vivo.

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2024-07-06
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