Nanostring gene expresson-based, antibody activation of bone marrow derived macrophages (BMDM)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE222466
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资源简介：
We study immune responses induced by amyloid targeting antibodies and CAA-mediated microhemorrhages using histology and gene expression analyses in AD mouse models and primary culture settings. We cultured and plated primary bone marrow-derived macrophages in wells coated with high Fc receptor activating antibody IgG2a or isotype control antibody harboring the LALAPG mutation, ablating Fc-FcR mediated effector functions To compare the transcriptional profiles for BMDM activated by Fc receptor signaling, isotype control antibody or non-treated.
创建时间：
2023-09-15
