Suppression of antitumor immunity by the oncometabolite 2-hydroxyglutarate

ChEBI2016-07-27 更新2026-07-12 收录

肿瘤代谢

肿瘤免疫学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-84849 数据链接链接失效反馈

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Suppression of antitumor immunity by the oncometabolite 2-hydroxyglutarate

创建时间：

2016-07-27

ProjecTILs human reference atlas of CD8+ tumor-infiltrating T cells, version 1

肿瘤免疫学

单细胞RNA测序

ProjecTILs human reference atlas of CD8+ tumor-infiltrating T cells, generated by semi-supervised STACAS integration of scRNA-seq datasets spanning 7 cancer types. The dataset is available as a S

DataCite Commons2025-06-01 更新250

Transcriptome analysis of tumor infiltrating NK and T cells in CT26-bearing BALB/C mice

肿瘤免疫学

肿瘤浸润淋巴细胞

CT26 tumors were implanted subcutaneously into syngeneic BALB/C mice and allowed to grow for 15-25 days. Tumors were collected, mechanically dissociated, and immune cells enriched using Percoll gradie

NIAID Data Ecosystem60

Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis

肿瘤代谢

线虫遗传学

c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth, cell proliferation, and differentiation. Myc initiates the transcription of a large cast of genes

NIAID Data Ecosystem40

Association between HPK1 expression and T-cell exhaustion. Association between HPK1 expression and T-cell exhaustion

肿瘤免疫学

T细胞耗竭

We aimed to investigate the association between HPK1 expression and exhausted status of tumor. Overall design: Bulk RNA-seq was performed on fresh-frozen tissue samples of renal cell carcinoma.

NIAID Data Ecosystem60

Data sheet index below 1.

功能基因组筛选

肿瘤代谢

In vitro and in vivo growth screen data, HCC827 cells, Source data for Fig 1. Mini-library CRISPRi screen in HCC827 cells, raw data. The read counts for each sgRNA in all in vitro and in vivo (flank a

Figshare2022-09-22 更新50

Suppression of antitumor immunity by the oncometabolite 2-hydroxyglutarate

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