Cortex-specific epigenetic profiling of chromatin accessibility after deeper cerebral hypoperfusion in mice

Efforts to understand genetic variability involved in cortex damage and glial activation support a role for upstream regulation by epigenetic mechanisms. To investigate cortex-specific epigenetic profiling after severe cerebral hypoperfusion in mice Cortex-specific epigenetic profiling analysis was performed using data obtained from ATAC-seq of 4 biological replicates in sham and BCAS mice after hypoperfusion