T cell impact rituximab-mediated NK cell transcriptomics
收藏NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE164086
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资源简介：
We found that T cells impacted rituximab-mediated NK cell viability, ability to mediate antibody dependent cellular cytotoxicity, and phenotypical changes in vitro. To understand the effects of T cells on ritxuimab-mediated NK cell responses at the transcriptional lvel, we performed bulk mRNA sequencing of NK cells in different experimental settings. Raji lymphoma cells were cocultured with unfractionated peripheral blood mononuclear cells (PBMC) or T cell-depleted PBMC for 7 days. NK cells were isolated from the coculture on day 7. mRNA was isolated from NK cells for bulk mRNA sequencing.
创建时间：
2021-07-14
