Shotgun Metagenomics of 361 post-menopause women reveals gut microbiome change along with the bone loss

The process that reabsorb calcium and phosphate from the bones instead of keeping these minerals just make our bones weaker, finally reach to the osteoporosis stage . The osteoporosis is a severe and common disease in elderly group, and it is the most common reason for fracture among the aged . Here wecarried out metagenomic shotgun sequencing to provide a detailed characterization of the compositional and functional features of gut microbiota change withe the bone loss .