Mean log reactivities of IgM and IgG serum antibodies binding to different antigens.

Healthy C57BL/6 mice manifest common autoantibody reactivities to some self-antigens and individual autoantibody reactivities to other self-antigens. Each reactivity was divided by the median reactivity of each sample and the log of the reactivities was taken. Thus, values lower than zero represent values lower than the median for the appropriate sample. The antigens were then divided by the variance of the log-reactivity over the healthy samples.