Native structure of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 7

Native structure of mosquitocidal Cyt1A protoxin obtained by Serial Femtosecond Crystallography on in vivo grown crystals at pH 7 Descriptor: SODIUM ION, Type-1Aa cytolytic delta-endotoxin Authors: Tetreau, G, Banneville, A.S, Andreeva, E, Brewster, A.S, Hunter, M.S, Sierra, R.G, Young, I.D, Boutet, S, Coquelle, N, Cascio, D, Sawaya, M.R, Sauter, N.K, Colletier, J.P. Deposit date: 2019-10-03 Release date: 2020-10-14 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Serial femtosecond crystallography on in vivo-grown crystals drives elucidation of mosquitocidal Cyt1Aa bioactivation cascade. Nat Commun, 11, 2020

通过在pH 7条件下对体内生长晶体开展串行飞秒晶体学（Serial Femtosecond Crystallography）解析获得的杀蚊Cyt1A原毒素天然结构。描述符：钠离子（SODIUM ION）、1Aa型溶细胞性δ-内毒素（Type-1Aa cytolytic delta-endotoxin）。作者：Tetreau G、Banneville A.S、Andreeva E、Brewster A.S、Hunter M.S、Sierra R.G、Young I.D、Boutet S、Coquelle N、Cascio D、Sawaya M.R、Sauter N.K、Colletier J.P。提交日期：2019-10-03；发布日期：2020-10-14；最后修改日期：2024-10-23。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.86 Å）。引用文献：《体内生长晶体的串行飞秒晶体学研究阐明杀蚊Cyt1Aa生物激活级联反应》，《自然-通讯》（Nat Commun），第11卷，2020年。