Impaired Natural Killer Cell Self-Education and 'Missing-Self' Responses in Ly49-Deficient Mice. Mus musculus

Nimblegen arrays were used to perform aCGH analysis on 2 mice strains, one which lacks the Ly49 gene cluster and the parent strain which still has the cluster. A targeted knock-out of the cluster resulted in the rearrangment and deletion of the cluster. The aCGH experiment was performed to elucidate the extent of the deletion. Overall design: high resolution aCGH analysis of the Ly49 cluster in deletion strain