Expression data from the dorsal root ganglia during streptozotocin-induced painful diabetic neuropathy in rats

We analyzed gene expression of the dorsal root ganglia together with measurement of mechanical allodynia in diabetic rats to try to capture the global fingerprint of changes in gene expression associated with FK1706 administration and also to elucidate the putative mechanisms of its neurotrophic activity in vivo.本研究对糖尿病大鼠的背根神经节（dorsal root ganglia）开展基因表达分析，并同步检测其机械性痛觉超敏（mechanical allodynia）水平，旨在捕捉与FK1706给药相关的基因表达变化的全局特征指纹，同时阐明其在体内发挥神经营养活性的推定作用机制。