Metal-Template-Controlled Stabilization of β‑Functionalized Isocyanides
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https://figshare.com/articles/dataset/Metal_Template_Controlled_Stabilization_of_Functionalized_Isocyanides/2452858
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资源简介：
Reaction of 2-azidoethyl isocyanide 1, 2-azidophenyl
isocyanide 2, or 2-nitrophenyl isocyanide 3 with complexes [Mo(CO)3(dppe)(py)] [4] or
[W(CO)3(dppe)(NCCH3)] [5] yields the isocyanide complexes [Mo(CO)3(dppe)(CNR)]
([6]: CNR = 1; [12]:
CNR = 2; [13]: CNR = 3) and [W(CO)3(dppe)(CNR)] ([7]: CNR = 1; [14]: CNR = 2; [15]: CNR = 3). Reduction
of the nitro or azido groups attached to the isocyanide ligands by
Zn/NH4Cl (azidoethyl or azidophenyl isocyanides) or Raney-nickel/hydrazine
hydrate (nitrophenyl isocyanide) yields exclusively the complexes
bearing the 2-amino-functionalized isocyanides. The normally unstable
2-amino-functionalized isocyanides are stabilized by M→CNR
back-bonding, which deactivates the isocyanide carbon atom for an
intramolecular nucleophilic attack by the primary amine.
创建时间：
2013-01-14
