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Histone modification changes during RASMCs' transformation into macrophage-like cells

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP557029
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We report histone modification status of H3K4me1, H3K4me2, H3K4me3 and H3K27ac within rat vascular smooth muscle cell at de-differentiated state (induced by DAPT treatment), inflammatory state (induced by cholesterol treatment) and macrophage-like state (induced by combined treatment of DAPT and cholesterol) Overall design: Primary rat aortic smooth muscle cells were treated by NOTCH inhibitor DAPT, soluble cholesterol or both of them for 48 hrs to achieve cell state transformations
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2025-05-30
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